Aloe

Drug Levels and Effects:




Summary of Use during Lactation:


Aloevera gel consists of the clear gel from the center of fresh leaves ofAloevera and relatedaloes. Active ingredients include mono- and poly-saccharides (e.g., acemannan, glucomannan), allantoin, enzymes (e.g., cyclooxygenase, amylase, lipase, alkaline phosphatase, carboxypeptidase), and salicylic acid. It should not be confused withAloelatex which comes from the inner portion of the skin and contains potent anthraquinone laxatives.Aloevera gel has been used topically on the nipples during nursing to help heal cracked nipples. In a randomized, single-blinded study (investigators blinded), aloe vera was more effective in decreasing nipple pain score after 7 days in women with sore nipples postpartum.[1] If aloe vera is applied to the nipples, it should be washed off before nursing the infant because the taste might adversely affect nursing or cause diarrhea in the infant.[2][3] No data exist on the safety and efficacy ofAloevera gel in nursing mothers or infants.Aloevera gel has caused itching, burning, and allergic contact dermatitis, possibly from contamination with the irritating latex from the leaves.[4][5]Aloevera gel also has an antiplatelet effect and can enhance the antiplatelet effect of other drugs.Aloelatex, the laxative, should not be used during breastfeeding.[6][7]

Dietary supplements do not require extensive pre-marketing approval from the US Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to prove the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does not certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products. More detailed informationabout dietary supplementsis available elsewhere on the LactMed Web site.


Drug Levels:


Maternal Levels.

Relevant published information was not found as of the revision date.

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


Relevant published information was not found as of the revision date.


Possible Effects on Lactation:


Relevant published information was not found as of the revision date.


References:


1. Tafazoli M, Saeedi R, Gholami Robatsangi M, Mazloom R. [Aloevera gel vs. lanolin ointment in the treatment of nipple sore: A randomized clinical trial]. Tehran Univ Med J. 2010;67:699-704.
2. Yarnell E . Botanical medicine in pregnancy and lactation. Altern Complement Ther. 1997;3 (April):93-100.
3. Larimore WL, Petrie KA. Drug use during pregnancy and lactation. Primary Care. 2000;27:35-53.
4. Barankin B, Gross MS. Nipple and areolar eczema in the breastfeeding woman. J Cutan Med Surg. 2004;8:126-30. PMID:15129318
5. De Smet PA. Health risks of herbal remedies: an update. Clin Pharmacol Ther. 2004;76:1-17. PMID:15229459
6. Kopec K. Herbal medications and breastfeeding. J Hum Lact. 1999;15:157-61. PMID:10578793
7. Nice F, Coghlan RJ, Birmingham BT. Which herbals are safe to take while breastfeeding? Here's a guide to popular herbs and their potential risk to nurslings. US Pharm. 2000;25.



Substance Identification:




Substance Name:

Aloe

Scientific Name:

Aloevera

CAS Registry Number:

8001-97-6

Drug Class:


  • Complementary Therapies

  • Phytotherapy

  • Plants, Medicinal


  • Administrative Information:




    LactMed Record Number:


    915


    Last Revision Date:


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