Bacampicillin

Drug Levels and Effects:




Summary of Use during Lactation:


Bacampicillin is acceptable to use during breastfeeding. Limited information indicates that maternal doses of bacampicillin of 500 mg produce low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally, disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush, has been reported with penicillins, but these effects have not been adequately evaluated.


Drug Levels:


Maternal Levels.

Only traces of drug could be detected in breastmilk after a 500 mg oral dose of bacampicillin in 2 women.[1]

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


Naproxen possibly caused prolonged bleeding time, thrombocytopenia and acute anemia in one 7-day-old infant in a mother also taking bacampicillin.[2] The role of bacampicillin in this reaction is unknown.


Possible Effects on Lactation:


Relevant published information was not found as of the revision date.


References:


1. Matsuda S. Transfer of antibiotics into maternal milk. Biol Res Pregnancy. 1984;5:57-60. PMID:6743732
2. Fidalgo I, Correa R, Gomez Carrasco JA et al. Anemia aguda, rectorragia y hematuria asociadas a la ingestion de naproxen. An Esp Pediatr. 1989;30:317-9. PMID:2787136



Substance Identification:




Substance Name:

Bacampicillin

CAS Registry Number:

50972-17-3

Drug Class:


  • Antiinfective Agents

  • Antibacterial Agents

  • Penicillins


  • Administrative Information:




    LactMed Record Number:


    23


    Last Revision Date:


    Disclaimer:Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.