Black Cohosh

Drug Levels and Effects:




Summary of Use during Lactation:


Black cohosh (</span>Cimicifugaracemosa, formerly Actaea racemosa) root was thought to have mild estrogenic activity based on its triterpene content, which is standardized based on 27-deoxyactein. However, recent studies have found no estrogenic activity.[1][2] It is primarily used for postmenopausal symptoms and has been used to promote labor.[3][4][5][6][7][8] Currently, it has no specific uses during breastfeeding, although historically it was supposedly used by native American women as a galactogogue.[9] No data exist on the safety and efficacy of black cohosh in nursing mothers or infants. In general, there is a low frequency of adverse reactions, but hepatitis and allergic reactions have been reported.[3][10] Some sources recommend against its use during breastfeeding because of the lack of safety data and its potential estrogenic activity,[10] while others do not contraindicate its use.[9]

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Drug Levels:


Maternal Levels.

Relevant published information was not found as of the revision date.

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


Relevant published information was not found as of the revision date.


Possible Effects on Lactation:


Relevant published information was not found as of the revision date.


References:


1. Liske E, Hanggi W, Henneicke-von Zepelin HH et al. Physiological investigation of a unique extract of black cohosh (Cimicifugae racemosae rhizoma): a 6-month clinical study demonstrates no systemic estrogenic effect. J Womens Health Gend Based Med. 2002;11:163-74. PMID:11975864
2. Ruhlen RL, Haubner J, Tracy JK et al. Black cohosh does not exert an estrogenic effect on the breast. Nutr Cancer. 2007;59:269-77. PMID:18001221
3. Dennehy C, Tsourounis C, Bui L, King TL. The use of herbs by California midwives. J Obstet Gynecol Neonatal Nurs. 2010;39:684-93. PMID:21044150
4. Zhang AL, Story DF, Lin V et al. A population survey on the use of 24 common medicinal herbs in Australia. Pharmacoepidemiol Drug Saf. 2008;17:1006-13. PMID:18816875
5. Dugoua JJ, Seely D, Perri D et al. Safety and efficacy of black cohosh (</span>Cimicifugaracemosa) during pregnancy and lactation. Can J Clin Pharmacol. 2006;13:e257-61. PMID:17085773
6. Allaire AD, Moos MK, Wells SR. Complementary and alternative medicine in pregnancy: a survey of North Carolina certified nurse-midwives. Obstet Gynecol. 2000;95:19-23. PMID:10636495
7. Low Dog T. The use of botanicals during pregnancy and lactation. Altern Ther Health Med. 2009;15:54-8. PMID:19161049
8. Tesch BJ. Herbs commonly used by women: an evidence-based review. Am J Obstet Gynecol. 2003;188:S44-55. PMID:12748451
9. McKenna DJ, Jones K, Humphrey S, Hughes K . Black cohosh: efficacy, safety, and use in clinical and preclinical applications. Altern Ther Health Med. 2001;7:93-100. PMID:11347288
10. Hardy ML. Women's health series: herbs of special interest to women. J Am Pharm Assoc (Wash). 2000;40:234-42 . PMID:10730024



Substance Identification:




Substance Name:

Black Cohosh

Scientific Name:

Cimicifugaracemosa

CAS Registry Number:

84776-26-1

Drug Class:


  • Complementary Therapies

  • Phytotherapy

  • Plants, Medicinal


  • Administrative Information:




    LactMed Record Number:


    872


    Last Revision Date:


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