Butabarbital

Drug Levels and Effects:




Summary of Use during Lactation:


Because there is little published experience with butabarbital during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.


Drug Levels:


Maternal Levels.

A mother who was 4 days postpartum had taken butabarbital 8 mg twice daily for 3.5 days. A milk level of 370 mcg/L was measured 1.5 hours after the previous dose.[1]

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


Relevant published information was not found as of the revision date.


Possible Effects on Lactation:


Relevant published information was not found as of the revision date.


Alternate Drugs to Consider:


Lorazepam,Oxazepam,Zaleplon,Zolpidem


References:


1. Horning MG, Stillwell WG, Nowlin J et al. Identification and quantification of drugs and drug metabolites in human breast milk using GC-MS-COM methods. Mod Probl Paediatr. 1975;15:73-9.



Substance Identification:




Substance Name:

Butabarbital

CAS Registry Number:

125-40-6

Drug Class:


  • Barbiturates

  • Hypnotics and Sedatives

  • GABA Modulators


  • Administrative Information:




    LactMed Record Number:


    492


    Last Revision Date:


    Disclaimer:Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.