Calendula

Drug Levels and Effects:




Summary of Use during Lactation:


Calendula(</span>Calendulaofficinalis) flowers contain triterpene glycosides and aglycones, carotenoids, and essential oils. Topical application of calendula products has been used to treat sore and cracked nipples during nursing, either in homeopathic or pharmacologic preparations,[1][2][3] although little high-quality evidence supports this use.[4] One uncontrolled case series found that a cream containing Mimosa tenuiflora andCalendulaofficinalis was useful for healing cracked nipples during breastfeeding;[5] however, the lack of a control group and the presence of another ingredient makes the evaluation of calendula 's efficacy impossible. Oral calendula has no specific lactation-related uses and no information is available on the oral use of calendula during breastfeeding.Calendulais "generally recognized as safe" (GRAS) as a food by the US Food and Drug Administration when used as a seasoning or flavoring. Allergic reactions, including cross-reactions to chrysanthemums, daisies and marigolds, occur rarely.

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Drug Levels:


Maternal Levels.

Relevant published information was not found as of the revision date.

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


Relevant published information was not found as of the revision date.


Possible Effects on Lactation:


Relevant published information was not found as of the revision date.


References:


1. Stapleton H. The use of herbal medicine in pregnancy and labour. Part II: Events after birth, including those affecting the health of babies. Complement Ther Nurs Midwifery. 1995;1:165-7. PMID:9456733
2. Kaplan B. Homoeopathy: 2. In pregnancy and for the under-fives. Prof Care Mother Child. 1994;4:185-7. PMID:8680189
3. Petrie KA, Peck MR. Alternative medicine in maternity care. Prim Care. 2000;27:117-36. PMID:10739460
4. Amir LH, Pirotta MV, Raval M. Breastfeeding - Evidence based guidelines for the use of medicines. Aust Fam Physician. 2011;40:684-90. PMID:21894275
5. Mucci M, Sciocchetti M, Benvenuti C. Clinical efficacy and safety of Mimosa tenuiflora bark extract in the rhagades of the nipple. G Ital Ostet Ginecol. 2006;28:106-14.



Substance Identification:




Substance Name:

Calendula

Scientific Name:

Calendulaofficinalis

CAS Registry Number:

84776-23-8 70892-20-5

Drug Class:


  • Complementary Therapies

  • Phytotherapy

  • Plants, Medicinal


  • Administrative Information:




    LactMed Record Number:


    940


    Last Revision Date:


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