Carbenicillin Indanyl Disodium

Drug Levels and Effects:




Summary of Use during Lactation:


Carbenicilin is acceptable to use during breastfeeding. Limited information indicates that maternal doses of carbenicillin produce low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally, disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush, has been reported with penicillins, but these effects have not been adequately evaluated.


Drug Levels:


Maternal Levels.

Milk levels have not been reported after oral doses of carbenicillin. After a single 1 gram intramuscular dose of carbenicillin in 3 women, milk levels averaged between 0.1 and 0.24 mg/L over the first 6 hours after the dose. Peak milk levels occurred 4 hours after the intramuscular dose.[1]

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


Relevant published information was not found as of the revision date.


Possible Effects on Lactation:


Relevant published information was not found as of the revision date.


References:


1. Matsuda S. Transfer of antibiotics into maternal milk. Biol Res Pregnancy. 1984;5:57-60. PMID:6743732



Substance Identification:




Substance Name:

Carbenicillin IndanylDisodium

CAS Registry Number:

4697-36-3

Drug Class:


  • Antiinfective Agents

  • Antibacterial Agents

  • Penicillins


  • Administrative Information:




    LactMed Record Number:


    39


    Last Revision Date:


    Disclaimer:Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.