Clotrimazole

Drug Levels and Effects:




Summary of Use during Lactation:


Because clotrimazole has poor oral bioavailability, it is unlikely to adversely affect the breastfed infant, including topical application to the nipples. It has been used orally in infants with thrush, sometimes successfully after nystatin has failed.[1] Any excesscreamor ointment should be removed from the nipples before nursing. Only water-misciblecreamor gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]


Drug Levels:


Maternal Levels.

Relevant published information was not found as of the revision date.

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


Relevant published information was not found as of the revision date.


Possible Effects on Lactation:


Relevant published information was not found as of the revision date.


Alternate Drugs to Consider:


Fluconazole,Miconazole,Nystatin


References:


1. Johnstone HA, Marcinak JF. Candidiasis in the breastfeeding mother and infant. J Obstet Gynecol Neonatal Nurs. 1990;19:171-3. PMID:2319366
2. Noti A, Grob K, Biedermann M et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003;38:317-25. PMID:14623482



Substance Identification:




Substance Name:

Clotrimazole

CAS Registry Number:

23593-75-1

Drug Class:


  • Antifungal Agents


  • Administrative Information:




    LactMed Record Number:


    346


    Last Revision Date:


    Disclaimer:Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.