Dexlansoprazole

Drug Levels and Effects:




Summary of Use during Lactation:


Dexlansoprazole is the

R

-enantiomer of the protein-pump inhibitor, lansoprazole. Because no information is available on the use of dexlansoprazole or lansoprazole during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.


Drug Levels:


Maternal Levels.

Relevant published information was not found as of the revision date.

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


Relevant published information was not found as of the revision date.


Possible Effects on Lactation:


One case of elevated serum prolactin and galactorrhea was reported in a 21-year-old man taking lansoprazole (the racemic form). Whenomeprazolewas substituted for lansoprazole, the serum prolactin decreased to the normal range and galactorrhea ceased.[1]


Alternate Drugs to Consider:


Cimetidine,Famotidine,Nizatidine,Omeprazole,Pantoprazole,Ranitidine,Sucralfate


References:


1. Izquierdo Prieto OM, Moreno Alia E, Rosillo Gonzalez A. [Galactorrhea induced by lansoprazole]. Aten Primaria. 2004;34:325-6. PMID:15491529



Substance Identification:




Substance Name:

Dexlansoprazole

CAS Registry Number:

138530-94-6

Drug Class:


  • Anti-Ulcer Agents


  • Administrative Information:




    LactMed Record Number:


    699


    Last Revision Date:


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