Dorzolamide

Drug Levels and Effects:




Summary of Use during Lactation:


Limited experience with the use of ophthalmic dorzolamide indicate that it is unlikely to adversely affect the breastfed infant. To substantially diminish the amount of drug that reaches the breastmilk after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.


Drug Levels:


Maternal Levels.

Relevant published information was not found as of the revision date.

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


A newborn infant was breastfed during maternal therapy with ocular timolol, dipivifrin, dorzolamide,brimonidineand several doses of acetazolamide. The drugs were given immediately following breastfeeding and no apnea or bradycardia was observed in the infant.[1]


Possible Effects on Lactation:


Relevant published information was not found as of the revision date.


References:


1. Johnson SM, Martinez M, Freedman S. Management of glaucoma in pregnancy and lactation. Surv Ophthalmol. 2001;45:449-54. PMID:11274697



Substance Identification:




Substance Name:

Dorzolamide

CAS Registry Number:

120279-96-1

Drug Class:


  • Antiglaucoma Agents

  • Carbonic Anhydrase Inhibitors


  • Administrative Information:




    LactMed Record Number:


    98


    Last Revision Date:


    Disclaimer:Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.