Doxazosin

Drug Levels and Effects:




Summary of Use during Lactation:


Because no information is available on the use of doxazosin during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.


Drug Levels:


Maternal Levels.

Relevant published information was not found as of the revision date.

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


Relevant published information was not found as of the revision date.


Possible Effects on Lactation:


Relevant published information in nursing mothers was not found as of the revision date. However, the pharmacologically similar drugprazosindoes not affect serum prolactin concentration in patients with hypertension.[1][2] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.


References:


1. Barbieri C, Caldara R, Ferrari C et al. Metabolic effects ofprazosin. Clin Pharmacol Ther. 1980;27:313-6. PMID:6102000
2. Barbieri C, Ferrari C, Borzio M et al. Metabolic effects of chronicprazosintreatment. Horm Metab Res. 1980;12:331-4. PMID:6105121



Substance Identification:




Substance Name:

Doxazosin

CAS Registry Number:

74191-85-8

Drug Class:


  • Adrenergic alpha-Antagonists

  • Antihypertensive Agents


  • Administrative Information:




    LactMed Record Number:


    745


    Last Revision Date:


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