Ethacrynic Acid

Drug Levels and Effects:




Summary of Use during Lactation:


Because no information is available on the use of ethacrynicacidduring breastfeeding and because intense diuresis might decrease lactation, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.


Drug Levels:


Maternal Levels.

Relevant published information was not found as of the revision date.

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


Relevant published information was not found as of the revision date.


Possible Effects on Lactation:


Ethacrynicacidwas reportedly used successfully to suppress lactation in 6 postpartum women who did not want to breastfeed and to decrease the intensity of milk production in another.[1] The added contribution of the diuretic to the other measures, which are effective in suppressing lactation, has not been studied. No data exist on the effects of loop diuretics on established, ongoing lactation.


Alternate Drugs to Consider:


Chlorothiazide,Hydrochlorothiazide


References:


1. Mahon R, Dubecq JP, Baudet E et al. [Use of Edecrine in obstetrics]. Bull Fed Soc Gynecol Obstet Lang Fr. 1968;20:440-2. PMID:5759113



Substance Identification:




Substance Name:

EthacrynicAcid

CAS Registry Number:

58-54-8

Drug Class:


  • Antihypertensive Agents

  • Loop Diuretics


  • Administrative Information:




    LactMed Record Number:


    106


    Last Revision Date:


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