Felbamate

Drug Levels and Effects:




Summary of Use during Lactation:


Because no information is available on the use of felbamate during breastfeeding, and because it can cause potentially fatal hematologic and hepatic toxicities, authors of authoritative reviews recommend that breastfeeding not be undertaken during maternal felbamate therapy until more safety data are available.[1][2]


Drug Levels:


Maternal Levels.

Relevant published information was not found as of the revision date.

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


Relevant published information was not found as of the revision date.


Possible Effects on Lactation:


Relevant published information was not found as of the revision date.


Alternate Drugs to Consider:


Dependent on the condition being treated.


References:


1. Bar-Oz B, Nulman I, Koren G et al. Anticonvulsants and breastfeeding. A critical review. Paediatr Drugs. 2000;2:113-26. PMID:10937463
2. Hagg S, Spigset O. Anticonvulsant use during lactation. Drug Saf. 2000;22:425-40. PMID:10877037



Substance Identification:




Substance Name:

Felbamate

CAS Registry Number:

25451-15-4

Drug Class:


  • Anticonvulsants


  • Administrative Information:




    LactMed Record Number:


    355


    Last Revision Date:


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