Fenoldopam

Drug Levels and Effects:




Summary of Use during Lactation:


No information is available on the use of fenoldopam during breastfeeding. Because of its poor oral bioavailability and short half-life, any fenoldopam in milk is unlikely to adversely affect the breastfed infant. Also, fenoldopam can be given intravenously to infants. Unlike dopamine, it does not decrease serum prolactin concentrations and might not interfere with nursing.


Drug Levels:


Maternal Levels.

Relevant published information was not found as of the revision date.

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


Relevant published information was not found as of the revision date.


Possible Effects on Lactation:


Relevant published information in nursing mothers was not found as of the revision date. Unlike dopamine, fenoldopam infusion does not affect serum prolactin concentration in normal women.[1] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.


Alternate Drugs to Consider:


(Hypertension) Enalapril,Hydralazine,Labetalol,Methyldopa,Propranolol


References:


1. Boesgaard S, Hagen C, Hangaard J et al. Pulsatile gonadotropin secretion and basal prolactin levels during dopamine D-1 receptor stimulation in normal women. Fertil Steril. 1991;55:281-6. PMID:1671361



Substance Identification:




Substance Name:

Fenoldopam

CAS Registry Number:

67227-56-9

Drug Class:


  • Antihypertensive Agents

  • Dopamine Agents

  • Dopamine Agonists

  • Vasodilator Agents


  • Administrative Information:




    LactMed Record Number:


    743


    Last Revision Date:


    Disclaimer:Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.