Ginseng

Drug Levels and Effects:




Summary of Use during Lactation:


The roots of American ginseng (Panax quinquefolius), Asian ginseng (Panax ginseng), and several other species contain steroidal saponins called ginsenosides that are purported to be adaptogens (i.e., to increase endurance and improve memory). Ginseng has no specific uses during breastfeeding. Ginseng is generally well tolerated in adults and is "generally recognized as safe" (GRAS) by the US Food and Drug Administration. The most common side effects include headache, hypertension, diarrhea, sleeplessness, skin rash, and vaginal bleeding and ginseng decreases the blood levels of some drugs, such as warfarin, and enhance the effect of sedating drugs. With long-term use, nervousness, diarrhea, confusion, depression or depersonalization may occur. Gynecomastia and breast pain have been reported.[1][2] No data exist on the safety and efficacy of ginseng in nursing mothers or infants. Because of its possible estrogenic activity and lack of information during breastfeeding, many sources recommend that ginseng not be used during lactation.

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Drug Levels:


Maternal Levels.

Relevant published information was not found as of the revision date.

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


Relevant published information was not found as of the revision date.


Possible Effects on Lactation:


Relevant published information was not found as of the revision date.


References:


1. Seely D, Dugoua JJ, Perri D et al. Safety and efficacy of Panax ginseng during pregnancy and lactation. Can J Clin Pharmacol. 2008;15:e87-94. PMID:18204104
2. Coon JT, Ernst E. Panax ginseng: a systematic review of adverse effects and drug interactions. Drug Saf. 2002;25:323-44. PMID:12020172



Substance Identification:




Substance Name:

Ginseng

Scientific Name:

Panax ginseng; Panax quinquefolius

CAS Registry Number:

50647-08-0; 92347-06-3

Drug Class:


  • Complementary Therapies

  • Phytotherapy

  • Plants, Medicinal


  • Administrative Information:




    LactMed Record Number:


    901


    Last Revision Date:


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