Indacaterol

Drug Levels and Effects:




Summary of Use during Lactation:


Although no published data exist on the use of indacaterol by mouth or inhaler during lactation, data from the related drug, terbutaline, indicate that very little is expected to be excreted into breastmilk.[1] The authors of several reviews agree that use of inhaled bronchodilators is acceptable during breastfeeding because of the low bioavailability and maternal serum levels after use.[2][3][4][5]


Drug Levels:


Maternal Levels.

Relevant published information was not found as of the revision date.

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


Relevant published information was not found as of the revision date.


Possible Effects on Lactation:


Relevant published information was not found as of the revision date.


References:


Lindberg C, Boreus LO, de Chateau P et al. Transfer of terbutaline into breast milk. Eur J Resp Dis Suppl. 1984;134:87-91. PMID:6586490
McDonald CF, Burdon JG. Asthma in pregnancy and lactation. A position paper for the Thoracic Society of Australia and New Zealand. Med J Aust. 1996;165:485-8. PMID:8937369
Ellsworth A. Pharmacotherapy of asthma while breastfeeding. J Hum Lact. 1994;10:39-41. PMID:7619245
Nelson-Piercy C. Asthma in pregnancy. Thorax. 2001;56:325-8. PMID:11254828
Taddio A, Ito S. Drugs and breast-feeding. In, Koren G, ed. Maternal-fetal toxicology. A clinician's guide. 3rd ed. New York. Marcel Dekker. 2001;177-32.



Substance Identification:




Substance Name:

Indacaterol

CAS Registry Number:

312753-06-3

Drug Class:


  • Anti-Asthmatic Agents

  • Beta Adrenergic Agonists

  • Bronchodilators


  • Administrative Information:




    LactMed Record Number:


    994


    Last Revision Date:


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