Iron Sucrose

Drug Levels and Effects:




Summary of Use during Lactation:


Limited data indicate that breastmilkironis not increased after intravenous infusion ofironsucrose. Amounts ofironingested by the infant would be normal and are not expected to cause any adverse effects in breastfed infants. No special precautions are required.


Drug Levels:


Maternal Levels.

Ten mothers who wereirondeficient 2 to 3 days postpartum received a single dose 100 mg of intravenousironsucrose. Theironconcentration in their colostrum was compared to those in 5 similar women who received noiron. Colostrum collected daily for 4 days after the injection contained averageironconcentrations between 0.3 and 0.45 mg/kg of milk which is in the low end of the range for postpartum women. No difference in milkironconcentration was found between the treated and control mothers.[1]

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


In a study of 104 women with postpartum anemia, 78 women received 300 mg of intravenousironsucrose over 3 days. All women were breastfeeding and had amenorrhea. No adverse reactions were reported in their infants.[2]


Possible Effects on Lactation:


Relevant published information was not found as of the revision date.


References:


1. Breymann C, von Seefried B, Stahel M et al. Milkironcontent in breast-feeding mothers after administration of intravenousironsucrosecomplex. J Perinat Med. 2007;35:115-8. PMID:17302514
2. Giannoulis C, Daniilidis A, Tantanasis T et al. Intravenous administration ofironsucrose for treating anemia in postpartum women. Hippokratia. 2009;13:38-40. PMID:19240819



Substance Identification:




Substance Name:

IronSucrose

CAS Registry Number:

8047-67-4

Drug Class:


  • Ferric Compounds

  • Hematinics


  • Administrative Information:




    LactMed Record Number:


    583


    Last Revision Date:


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