Lavender (Lavendula angustifolia) flowers, leaves andoilcontain linaloyl acetate, linalool, perillyl alcohol, 1,8 cineole (eucalyptol), and at least 100 other known compounds. Lavender has no specific lactation-related uses. Lavender preparations have traditionally been used for anxiety and other neurologic conditions, infections, pain and a variety of other conditions, often as aromatherapy. None of these uses have good scientific evidence to support their use. Lavender is "generally recognized as safe" (GRAS) as a food by the US Food and Drug Administration. In general, lavender is well tolerated, but no data exist on the excretion of any components of lavender into breastmilk or on the safety and efficacy of lavender in nursing mothers or infants. Lavenderoilmay have some minor estrogenic and antiandrogenic activity, so topical application around the breast should be avoided.
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Twelve nursing mothers who were19 weeks to 19 months postpartum ingested 100 mg of 1,8 cineole (eucalyptol) in the form of delayed-release capsules (Soledum-Klosterfrau Vertriebs GmbH, Germany) that release the drug in the intestine. Then they pumped 1 to 4 milk samples at the time they perceived the smell of eucalyptus on their breath which had been previously shown to be approximately concurrent. A total of 21 milk samples were obtained. Odor was rated by a panel of 3 to 5 experts as either smelling like eucalyptus or not. Fourteen of the samples had a distinct eucalyptus-like odor. Chemical analysis of the positive odor tests found 1,8-cineole in concentrations from 70 to about 2090 mcg/kg of milk, most in the range of 100 to 500 mcg/kg of milk. Samples with negative odor tests contained concentrations in the range of 0.98 to about 20.23 mcg/kg of milk. In one woman who donated 3 samples, the highest concentration of 71 mcg/kg occurred at 1.5 hours after ingestion, with concentrations of 1 mcg/kg before ingestion and 15 mcg/kg at 9.5 hours after ingestion.
Relevant published information was not found as of the revision date.
Effects in Breastfed Infants:
Nursing mothers who were participating in an experiment on the excretion of 1,8-cineole (eucalyptol) in breastmilk took a 100 mg capsule of 1,8-cineole orally. Although instructed not to, 12 mothers breastfed their infants during the experiment. Mothers reported that none of their infants refused their milk or breastfed less than usual. Two mothers felt that their infants were more agitated a few hours after breastfeeding. A third mother reported that the infant stopped nursing from time to time and "looked puzzled", but resumed nursing. Upon repeating the experiment 6 weeks later, the infant did not react in an unusual way during breastfeeding.
Possible Effects on Lactation:
Gynecomastia occurred in 3 prepubertal boys who were using grooming products containing lavenderoil. The gynecomastia resolved after the products were discontinued. In vitro testing found that lavenderoilpossesses mild estrogenic and antiandrogenic activity. The relevance of these finding has been questioned, but no further testing has been reported to confirm or refute the findings as of the revision date.
1. Kirsch F, Beauchamp J, Buettner A. Time-dependent aroma changes in breast milk after oral intake of a pharmacological preparation containing 1,8-cineole. Clin Nutr. 2012. PMID:22405404 2. Henley DV, Lipson N, Korach KS, Bloch CA. Prepubertal gynecomastia linked to lavender and tea treeoils. N Engl J Med. 2007;356:479-85. PMID:17267908 3. Kemper KJ, Romm AJ, Gardiner P. Prepubertal gynecomastia linked to lavender and tea treeoils. N Engl J Med. 2007;356:2541-2; author reply 2543-4. PMID:17568039 4. Kalyan S. Prepubertal gynecomastia linked to lavender and tea treeoils. N Engl J Med . 2007;356:2542; author reply 2543-4. PMID:17575592
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