Meningococcal Vaccines

Drug Levels and Effects:




Summary of Use during Lactation:


The Centers for Disease Control and Prevention and several health professional organizations state that vaccines given to a nursing mother do not affect the safety of breastfeeding for mothers or infants and that breastfeeding is not a contraindication to meningococcal vaccine. Breastfed infants should be vaccinated according to the routine recommended schedules.[1][2][3]


Drug Levels:


Maternal Levels.

Relevant published information was not found as of the revision date.

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


Limited data indicate that breastfeeding can enhance the response of the infant to certain vaccine antigens.[1][3][4]

Immunization of pregnant or lactating women with meningococcal vaccine increased the specific secretory IgA content of milk.[5][6]


Possible Effects on Lactation:


Relevant published information was not found as of the revision date.


References:


1. General recommendations on immunization --- recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2011;60 (RR-2):1-64. PMID:21293327
2. Gruslin A, Steben M, Halperin S et al. Immunization in pregnancy: No. 220, December 2008. Int J Gynaecol Obstet. 2009;105:187-91. PMID:19367691
3. Anon. Human milk. In: Pickering LK, Baker CJ, Kimberlin DW, Long SS, eds. Red Book: 2009 Report of the Committee on Infectious Diseases. 28th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2009.
4. Pabst HF. Immunomodulation by breast-feeding. Pediatr Infect Dis J. 1997;16:991-5. PMID:9380478
5. Lakshman R, Seymour L, Akhtar S et al. Secretory antibody responses to quadrivalent meningococcal vaccine in lactating mothers. Clin Infect Dis. 2000;31(1):321. Abstract 629.
6. Shahid NS, Steinhoff MC, Roy E et al. Placental and breast transfer of antibodies after maternal immunization withpolysaccharidemeningiococcal vaccine: a randomized, controlled evaluation. Vaccine. 2002;20:2404-9. PMID:12009297



Substance Identification:




Substance Name:

Meningococcal Vaccines

Drug Class:


  • Vaccines


  • Administrative Information:




    LactMed Record Number:


    168


    Last Revision Date:


    Disclaimer:Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.