Methyclothiazide

Drug Levels and Effects:




Summary of Use during Lactation:


If methyclothiazide is required by the mother, it is not a reason to discontinue breastfeeding. Intense diuresis with large doses may decrease breastmilk production.


Drug Levels:


Maternal Levels.

Relevant published information was not found as of the revision date.

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


Relevant published information was not found as of the revision date.


Possible Effects on Lactation:


Relevant published information on methyclothiazide was not found as of the revision date. Intense diuresis with thiazides and thiazide-like diuretics, fluid restriction and breast binding have been used to suppress postpartum lactation.[1][2][3] The added contribution of the diuretic to these measures, which are effective in suppressing lactation, has not been studied. There are no data on the effects of diuretics on established, ongoing lactation.


Alternate Drugs to Consider:


Chlorothiazide,Hydrochlorothiazide


References:


1. Healy M. Suppressing lactation with oral diuretics. Lancet. 1961;277:1353-4.
2. Reiher KH. [Suppression of lactation by stimulation of diuresis] . Zentralbl Gynakol. 1963;85:188-90. PMID:13973786
3. Stout G. Suppression of lactation. Br Med J. 1962;1:1150. Letter.



Substance Identification:




Substance Name:

Methyclothiazide

CAS Registry Number:

135-07-9

Drug Class:


  • Antihypertensive Agents

  • Thiazide Diuretics


  • Administrative Information:




    LactMed Record Number:


    178


    Last Revision Date:


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