Phenelzine

Drug Levels and Effects:




Summary of Use during Lactation:


Because of the lack of data on use during breastfeeding, other antidepressants are preferred during breastfeeding.


Drug Levels:


Maternal Levels.

Relevant published information was not found as of the revision date.

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


Relevant published information was not found as of the revision date.


Possible Effects on Lactation:


Phenelzine can elevate serum prolactin in some patients[1] and has caused galactorrhea in nonpregnant, nonnursing patients.[2] The clinical relevance of these findings in nursing mothers is not known. The prolactin level in a mother with established lactation may not affect her ability to breastfeed.


Alternate Drugs to Consider:


Nortriptyline,Paroxetine,Sertraline


References:


Coker F, Taylor D. Antidepressant-induced hyperprolactinaemia: incidence, mechanisms and management. CNS Drugs. 2010;24:563-74. PMID:20527996
1. Segal M, Heys RF. Inappropriate lactation. Br Med J. 1969;4:236. PMID:5388733



Substance Identification:




Substance Name:

Phenelzine

CAS Registry Number:

51-71-8

Drug Class:


  • Antidepressants

  • Monoamine Oxidase Inhibitors


  • Administrative Information:




    LactMed Record Number:


    310


    Last Revision Date:


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