Quniupristin-Dalfopristin

Drug Levels and Effects:




Summary of Use during Lactation:


Quinupristin and dalfopristin are relatively large molecules that are unlikely to be excreted into breastmilk in large amounts or to be absorbed orally by the breastfeeding infant.[1] If quinupristin-dalfopristin is required by the mother, it is not a reason to discontinue breastfeeding. However, since no information is available on the use of quinupristin and dalfopristin during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.


Drug Levels:


Maternal Levels.

Relevant published information was not found as of the revision date.

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


Relevant published information was not found as of the revision date.


Possible Effects on Lactation:


Relevant published information was not found as of the revision date.


Alternate Drugs to Consider:


Clindamycin,Doxycycline,Linezolid,Trimethoprim-Sulfamethoxazole,Vancomycin


References:


1. Chin KG, Mactal-Haaf C, McPherson CE III. Use ofanti-infective agents during lactation: part 1 -- beta-lactam antibiotics, vancomycin, quinupristin-dalfopristin, and linezolid. J Hum Lact. 2000;16:351-8. PMID:11155614



Substance Identification:




Substance Name:

Quniupristin-Dalfopristin

CAS Registry Number:

126602-89-9

Drug Class:


Anti
  • -Bacterial Agents

  • Anti
  • -Infective Agents

  • Protein Synthesis
  • Inhibitors

    Administrative Information:




    LactMed Record Number:


    889


    Last Revision Date:


    Disclaimer:Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.