Tiagabine

Drug Levels and Effects:




Summary of Use during Lactation:


Monitor the infant for drowsiness, adequate weight gain, and developmental milestones, especially in younger, exclusively breastfed infants and when using combinations of anticonvulsant or psychotropic drugs. Because there is no published experience with tiagabine during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.


Drug Levels:


Maternal Levels.

Relevant published information was not found as of the revision date.

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


One mother successfully breastfed her infant while taking tiagabine 24 mg and then 20 mg daily.[1]


Possible Effects on Lactation:


Relevant published information was not found as of the revision date.


Alternate Drugs to Consider:


Dependent on the condition being treated.


References:


1. Neppe VM. Successful tiagabine monotherapy during pregnancy and lactation: clinical and serum data. Epilepsia. 2000;41 (Suppl 7):200-1. Abstract.



Substance Identification:




Substance Name:

Tiagabine

CAS Registry Number:

115103-54-3

Drug Class:


  • Anticonvulsants

  • GABA Agonists

  • Neurotransmitter Uptake Inhibitors

  • Neuroprotective Agents


  • Administrative Information:




    LactMed Record Number:


    389


    Last Revision Date:


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