Tretinoin

Drug Levels and Effects:




Summary of Use during Lactation:


Topical tretinoin has not been studied during breastfeeding. Because it is poorly absorbed after topical application, it is considered a low risk to the nursing infant.[1][2] Ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[3]


Drug Levels:


Maternal Levels.

Relevant published information was not found as of the revision date.

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


Relevant published information was not found as of the revision date.


Possible Effects on Lactation:


Relevant published information was not found as of the revision date.


Alternate Drugs to Consider:


(Acne) Azelaic Acid,BenzoylPeroxide,Clindamycin,Erythromycin


References:


1. Leachman SA, Reed BR. The use of dermatologic drugs in pregnancy and lactation. Dermatol Clin. 2006;24:167-97. PMID:16677965
2. Zip C. Common sense dermatological drug suggestions for women who are breast-feeding. Skin Therapy Lett. 2002;7:5-7. PMID:12007012
3. Noti A, Grob K, Biedermann M et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003;38:317-25. PMID:14623482



Substance Identification:




Substance Name:

Tretinoin

CAS Registry Number:

302-79-4

Drug Class:


  • Antineoplastic Agents

  • Dermatologic Agents

  • Keratolytic Agents

  • Retinoids


  • Administrative Information:




    LactMed Record Number:


    539


    Last Revision Date:


    Disclaimer:Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.