Tuberculin

Drug Levels and Effects:




Summary of Use during Lactation:


There is no reason to withhold breastfeeding after tuberculosis skin testing or to avoid skin testing in nursing mothers.


Drug Levels:


Maternal Levels.

Relevant published information was not found as of the revision date.

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


There is some evidence that breastfed infants can acquireimmuneresponsiveness to tuberculin via breastmilk.[1][2][3] However, other investigators have found no evidence of breastmilk transfer of immunity.[4]


Possible Effects on Lactation:


Relevant published information was not found as of the revision date.


References:


1. Martinez-Cairo Cueto S, Alasio-Chavez C, Davila Velasquez JR. [In vitro transfer of immunity against PPD with dialyzable extract of leukocytes from human colostrum]. Rev Alerg. 1992;39:126-32. PMID:1492196
2. Schlesinger JJ, Covelli HD. Evidence for transmission of lymphocyte responses to tuberculin by breast-feeding. Lancet. 1977;2:529-32. PMID:95733
3. Masters PL. Maternal transmission of skin sensitivity to tuberculin. Lancet. 1982;2:276-7. PMID:6124704
4. Keller MA, Rodgriguez AL, Alvarez S et al. Transfer of tuberculin immunity from mother to infant. Pediatr Res.1987;22:277-81. PMID:3658548



Substance Identification:




Substance Name:

Tuberculin

CAS Registry Number:

92129-86-7

Drug Class:


  • Antigens

  • Purified
  • Protein Derivative


  • Administrative Information:




    LactMed Record Number:


    273


    Last Revision Date:


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