Varenicline

Drug Levels and Effects:




Summary of Use during Lactation:


Varenicline is a partial nicotine agonist used to assist smoking cessation. One researcher points out that based on animal data on nicotine, varenicline might interfere with normal infant lung development and recommends against its use in nursing mothers.[1] Because no information is available on the use of varenicline during breastfeeding, an alternate drug is preferred, especially while nursing a newborn or preterm infant.


Drug Levels:


Maternal Levels.

Relevant published information was not found as of the revision date.

Infant Levels.

Relevant published information was not found as of the revision date.


Effects in Breastfed Infants:


Relevant published information was not found as of the revision date.


Possible Effects on Lactation:


Relevant published information was not found as of the revision date.


Alternate Drugs to Consider:


(Smoking Cessation)Bupropion


References:


1. Maritz GS. Are nicotine replacement therapy, varenicline orbupropionoptions for pregnant mothers to quit smoking? Effects on the respiratory system of the offspring. Ther Adv Respir Dis. 2009. PMID:19706643



Substance Identification:




Substance Name:

Varenicline

CAS Registry Number:

249296-44-4

Drug Class:


  • Nicotinic Agonists


  • Administrative Information:




    LactMed Record Number:


    784


    Last Revision Date:


    Disclaimer:Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.